Stack for a female

does she want to grow? or does she want to lean out?

She wants to grow a little more but basically wants to lean out a little more for the summer but of course wants to keep the gains she has achieved.

From reading this...absolutely DO NOT put your girl on testosterone. Unless you are a hardcore bodybuilder this is not a route you want to experiment with...especially as a female.

From reading this...absolutely DO NOT put your girl on testosterone. Unless you are a hardcore bodybuilder this is not a route you want to experiment with...especially as a female.

she's 32 (i believe that's what i read) her hormone levels have dropped, therefore, putting her on small dosages of test shouldn't bother her too much. it will probably work as a HRT for her.

i was 30ish when i started using test and have NEVER felt better. it regulated my hormone levels immensely, put a stop to my "pms" symptoms, made my peroid a little irregular (again though, i was using very LARGE amounts of test)

IMO, small dosages of test are a good HRT for women in their 30's.

if you want to try something COMPLETELY different, put her on a few gms of trib a day, it takes awhile to kick in, but trib will regulate hormones as well and do it NATURALLY. she will make gains from it as well.....

50mgs of test (propionate) a week isn't that big of a dose, you could always start her out smaller (25mgs a week~12.5mgs X 2) but from the above posts, she has used a few compounds already, therefore, i wouldn't be concerned with 50mgs a week (25mgs X 2) if she ran 150mgs a week already, im sure she wouldn't run into problems running 50mgs.

Thanks for clearing that up Queenie!

You were right that was a great stack for her. Awesome gains in her back and arms!

How long should she stay off before restarting another cycle?

barcardi, QOD, & Avon,
wow what a thread, I'm glad it worked out for you avon, Lets hope i can have the same success. Ok Here goes. Avon has done basically what i hope to do. Can you all recommend something this way. First what is trib? thats one I couldnt figure out.
I've been training for about 3 years serious for over a year. Tried my first round with Winnie and prima. Went pretty well as i was trying to put on some size. I did my first diet and thats when things really showed up. I"m having a really hard time losing my stomach. I was on a strict diet and followed it religiously and did my cardio religiously but my stomach did not go away. I was on this diet 12 weeks and had already ran my first and only cycle. So I'm hoping to diet again and this time with assistance and hopefully with your knowledge get rid of the remainder of body fat that didnt dissappear the first time around while at the same time keeping the muscle and size I've attained.

thanks for any help
Rabit

can you give us some idea of how your caloric breakdown is on your diet? what kind of training/cardio you do? this information will help tons:)

QOD

QOD

as far as caloric breakdown/ taking in about 1800 calories a day
200-230 g protein/ 160-170 carbs/ 20g fat/sodium 1200 g

o.n. protein shake and 1/2 to 3/4 c oatmeal breakfast (5:00)
o.n. mrp 9:30
6oz chicken and 6oz potato 11:30
o.n. mrp 2:30
6oz chicken and 6oz potato at dinner and that is usually about 8:00 pm
gal or more of water a day
coffee with half and half and equal

this pretty much makes up my diet

workout schedule is:
sat chest/flat bench 115 3/10 w/backoff set
incline bench 105 3/10
inclline dumbell 30 3/10
decline freeweight 65 3/10
flat dumbell 30 3/10
sun back/ hyper 50 3/10
lat pull 10/8/6/4/& 3/3 starting at 70 to 110 with backoff 55 1/20
t bars 80 3/10
rack pulls 155 3/10 with backoff 95 1/20
tue shoulders/ the weak part of my body
smith military press 80 3/10
db military press 20 3/10
front delt raises 8 3/10
side delt raises 10 3/10
rear delt raises 5 3/10
db shrugs 40 3/15
thur arms/
camber curls 20 3/10
straight bar curl 30 3/10
one arm cable curl 10 3/10
bicep curl 30 3/10
tricep p.down 10/8/6/4/& 3/3
starting with 42.5 to62.5 with backoff 1/20
one arm tricep push downs 12 3/10
tricep extensions seated 15 3/10
fri legs/ (i hate legs 🙂 )
v squat 180 3/10 wide
v squat 90 2/20 close
leg extensions 70 3/10
stiff legged deads 50 3/10
lying hams 15 3/15
seated hams 50 3/15

doing abs 3 days a week minimum
cable crunches 42.5 3/20
seated crunches 20 3/20
decline crunches 3/15
cardio 5 days a week at lunch before eating 30 min= about a mile.

I think this is about everything, oh yeah we take a handful of vitamins every morning

thanks again for everything.

Bumping back up....

How long should she stay off before restarting another cycle?

Bumping back up....

rule of thumb is time on = time off.....i think it depends on age and experience though, im a bit older and have never followed the "golden rule"

your body is constantly producing new receptor sites via training and AAS use. there is no truth about "destroying" receptor sites from over usage of AAS, that's just bullshit.

if she has tapered right, i would say give her 8-10 weeks and try another, better safe than sorry:)

QOD

as far as caloric breakdown/ taking in about 1800 calories a day
200-230 g protein/ 160-170 carbs/ 20g fat/sodium 1200 g

o.n. protein shake and 1/2 to 3/4 c oatmeal breakfast (5:00)
o.n. mrp 9:30
6oz chicken and 6oz potato 11:30
o.n. mrp 2:30
6oz chicken and 6oz potato at dinner and that is usually about 8:00 pm
gal or more of water a day
coffee with half and half and equal

this pretty much makes up my diet

workout schedule is:
sat chest/flat bench 115 3/10 w/backoff set
incline bench 105 3/10
inclline dumbell 30 3/10
decline freeweight 65 3/10
flat dumbell 30 3/10
sun back/ hyper 50 3/10
lat pull 10/8/6/4/& 3/3 starting at 70 to 110 with backoff 55 1/20
t bars 80 3/10
rack pulls 155 3/10 with backoff 95 1/20
tue shoulders/ the weak part of my body
smith military press 80 3/10
db military press 20 3/10
front delt raises 8 3/10
side delt raises 10 3/10
rear delt raises 5 3/10
db shrugs 40 3/15
thur arms/
camber curls 20 3/10
straight bar curl 30 3/10
one arm cable curl 10 3/10
bicep curl 30 3/10
tricep p.down 10/8/6/4/& 3/3
starting with 42.5 to62.5 with backoff 1/20
one arm tricep push downs 12 3/10
tricep extensions seated 15 3/10
fri legs/ (i hate legs 🙂 )
v squat 180 3/10 wide
v squat 90 2/20 close
leg extensions 70 3/10
stiff legged deads 50 3/10
lying hams 15 3/15
seated hams 50 3/15

doing abs 3 days a week minimum
cable crunches 42.5 3/20
seated crunches 20 3/20
decline crunches 3/15
cardio 5 days a week at lunch before eating 30 min= about a mile.

I think this is about everything, oh yeah we take a handful of vitamins every morning

thanks again for everything.

as you will find out on this board, im not a big fan of carbohydrate dieting (especially for women) i diet moderate fats (efa's) and zero carbs. i keep my protein intake very high (300gms a day)

im not sure that you are getting enough calories though. what is your height? weight? i am eating 1800calories a day and am pre-contest (and not very big) can you fill me in on that?

are you rotating your carbs? it is my understanding that dieting on carbs requires a rotation in order to keep your body from "adapting" to the diet. you see, i diet on under 30gms of carbs a day, so, once a week, i get a junk day where i can eat whatever i want, it's sweet!

Thanks..

I am 41 5'0 even and weigh 120 lbs. and thats because my weight has started creeping again. I am peri-menopausal.
I havent varied my carbs very much at all, and that could be part of the reason my weights creeping. what do you think?

I could really use your help. I know I probably will never compete nationally but I would like to do a national qualifying show at least once.

thanks

I am 41 5'0 even and weigh 120 lbs. and thats because my weight has started creeping again. I am peri-menopausal.
I havent varied my carbs very much at all, and that could be part of the reason my weights creeping. what do you think?

I could really use your help. I know I probably will never compete nationally but I would like to do a national qualifying show at least once.

thanks

a small amount of test will help with the "menopausal" problem. women tend to gain weight when going through "the change" it whacks your hormones out therefore causing numerous problems within the body (dryness, weight gain, mood swings, etc.)

test will bring up your estrogen levels, im not talking huge amounts either, 50 mgs a week of cypionate (taken 2 X 25mgs) will do the job, without the risks involved with using synethetic estrogen, such as heart disease, stroke, etc. synthetic estrogen can be very dangerous and has been proven to be a problem. synthetic Testosterone however causes none of the above mentioned problems, and remember, it's not just your estrogen levels that are dropping, it's your natural testosterone as well (this would lead to lack of sex drive, dryness, etc)

now, to go the "natural" route, again, i will preach the joys of tribulus. i have just recently put a menopausal woman who is suffering from terrible night sweats on 3gms a day. within 2 weeks, she was noticing a difference, they are decreasing (night sweats) and she is feeling alot better.

you can pick up tribulus from any health food store, it usually comes in 1500mg pills, i suggest the same dose (3gms a day) as she is a small woman as well.

i hope this helps, sorry for the delay in answering...

QOD

here's a good read on tribulus, it's a long one though.....

Tribulus for sexual dysfunction in men and women

Kerry Bone
Introduction

Tribulus terrestris (puncture vine) is a prostrate, spreading herb particularly adapted to dry regions which produces a fruit with sharp, rigid spines (hence the common name). It is regarded as a problematic weed in some parts of the world and excessive consumption by livestock can lead to disruption of normal bile excretion (see later under Toxicology).

[ILLUSTRATION OMITTED]

The entire plant, but particularly the fruit is used in traditional medicine. In Ayurveda, Tribulus fruit or root, known as Gokshura, is used mainly for diseases of the urinary system (cystitis, painful urination, kidney stones, edema) and of the reproductive system (spermatorrhea, gonorrhea, impotence and uterine disorders after parturition). It is also used to treat gout, coughs and heart disease and is regarded as a diuretic with antiseptic and soothing activity on the mucous membranes of the urinary tract. The entire plant, including the root is also used. (1-3)

In Traditional Chinese Medicine the fruit of Tribulus is used for skin lesions with itching, for pain and distension in the chest, insufficient lactation due to constrained liver Qi and for swollen, painful eyes. (4)

In recent years, much attention has focused on the Bulgarian research on a Tribulus herb product used as a male tonic and for the treatment of infertility and menopausal symptoms. The information in this monograph is mainly centered on this recent research.

Key Constituents

The key constituents of Tribulus leaf include the steroidal saponins, mainly furostanol glycosides (including protodioscin and protogracillin) and small quantities of spirostanol glycosides. (5-7) Other constituents include phytosterols (e.g. [beta]-sitosterol), (8) and perhaps very small quantities of harmala alkaloids (tryptophanderived [beta]-carbolines) which may only occur in some varieties (9) and have not been found in some investigations. (10) Tribulus leaf contains higher concentrations of steroidal saponins than the fruit.

The furostanol glycosides are a subclass of steroidal saponins. They have a sugar group at the carbon-3 (C-3) position and a second sugar group at position C-26. Furostanol glycosides readily convert into spirostanol saponins (with one sugar group at C-3) in the presence of plant enzymes. (11) Such degradation, resulting in loss of sugars, may occur postharvest, in manufacturing or during experimental analysis.

Tribulus leaf standardized extract (TLSE) is a product obtained from the aerial parts of Tribulus terrestris, which contains mainly saponins of the furostanol type (not less than 45%, calculated as protodioscin) which was developed in Bulgaria from Mediterranean varieties of Tribulus.

Pharmacodynamics

Hormonal and Sexual Activity

Oral doses of TLSE have demonstrated the following effects in vivo:

** Marked stimulation of spermatogenesis, increased density of Sertoli cells, increased tenacity and viability of spermatozoa, and accelerated and emphasized sexual activity in rats (70 mg/kg/day). (12) Female rats treated with the saponin fraction produced more offspring. (6)

** Increased plasma testosterone concentrations compared to controls in male lambs and rams (250 mg/day); acceleration of sexual development, activation of spermatogenesis and stimulation of seminiferous tubule growth in immature sheep. (13)

** Increased testosterone levels, improved semen production and normalized sexual activity in rams with sexual impotence; no morphologic changes in the structure of either testes or epididymides were observed during the treatment period. (14)

** Restored libido and sexual reflexes in 71% of boars suffering absence of libido. Five animals with prolonged poor libido also improved (70 mg/kg/day). (15)

** Aphrodisiac activity in a rat model, which was attributed to an androgenic effect (5 mg/kg/day orally). (16)

** A dose-dependent increase in body weight, penile intracavernous pressure (related to improved erectile function) and sexual activity in rats given oral doses ranging from 2.5 to 10 mg/kg/day. (17)

Tonic and Adaptogenic Activity

TLSE increased the nonspecific resistance in mice with experimental lung infection. The protective effect was based on the activation of alveolar macrophages. (18) Studies indicate that TLSE intensifies protein synthesis and enhances the activity of some enzymes connected with energy metabolism. (19)

TLSE (oral; 100 mg/kg/day for 5 days) increased static physical endurance in rats. Treatment with a related formulation (oral; 300 mg/kg/day for 1 month) markedly increased endurance and (by injection) accelerated the restoration process after heavy exercise. (20) The mechanism of improved endurance was probably not directly connected with the adrenergic system. The preparation did not stimulate the CNS and its mechanism of action was different from that of psychostimulants. (19,20) The same formulation improved resistance to stress and endurance in vivo compared to controls. It increased the concentration of dopamine and serotonin metabolites and the levels of noradrenaline in the hypothalamus. (21)

Pharmacokinetics

Pharmacokinetic studies of TLSE in rats indicated that 12 to 14% of administered protodioscin is excreted in the bile and 6 to 7% in the urine (at 24 hours) when delivered intravenously (50 and 200 mg/kg). After oral administration of the same individual doses, 2 to 4% of protodioscin was apparently excreted in the bile, but protodioscin was not detected in the urine. (22) However, the researchers may have mistaken glucuronide conjugates of furostanol aglycones for protodioscin (see Toxicology below).

Toxicology

LD50 values for acute oral administration of TLSE in both mice and rats were greater than 10 g/kg, indicating very low toxicity. No lethality, change in behavior or changes in biochemical indices were observed in rats orally administered doses ranging from 75 mg/kg to 300 mg/kg for 30 and 90 days, or dogs receiving 75 mg/kg for 180 days. (23) Oral administration of TLSE at 50 mg/kg/day or 150 mg/kg/day for 93 weeks did not induce evidence of carcinogenicity. (24)

Consumption of Tribulus by livestock, especially sheep, has lead to the photosensitization syndrome known as geeldikkop (yellow thick head) in South Africa, Australia and Argentina. (25-27) The ingested saponins are rapidly hydrolyzed in the rumen, releasing free sapogenins. Most of the sapogenins (especially diosgenin and yamogenin) are rapidly converted by ruminal microflora to epismilagenin and episarsapogenin which are absorbed. These are conjugated with glucuronic acid in the liver and excreted in the bile as calcium salts of the sapogenin glucuronides. These salts are insoluble in high amounts and precipitate in the bile ducts as crystals. The resultant disruption of bile excretion results in retention of phylloerythrin (a photodynamic chlorophyll metabolite) and induction of photosensitization. (27) This reaction has not been observed in humans and is unlikely, given the large quantities needed to trigger this process and the unique link with ruminant digestive flora.

Ingestion of Tribulus can also cause a unique neuromuscular disorder in sheep, known as tribulus staggers which has been attributed to the accumulation of the harmala alkaloids in the blood over a period of time. (9) This has not been observed in humans and is highly unlikely at the recommended dosage. Also the presence of harmala alkaloids in Tribulus is disputed. (10)

Clinical Studies

Male Infertility and Impotence

The results of open clinical trials conducted by four Bulgarian research teams, including a total of 363 men, indicated that TLSE had a stimulating effect on sexual function. (28-32)

** Treatment with 750 mg for 60 days significantly increased motility and rate of movement of spermatozoa from 38 men with idiopathic oligospermia. In some cases, after repeated treatment at a dosage of 1500 mg/day, a normalization of the sperm profile was observed, accompanied by an increased serum level of LH and testosterone and decreased estradiol.

** Two groups of men with oligospermia after varicocele operation were treated with either 750 mg for 60 days or 1500 mg for 90 days. Significant improvement in sperm motility was observed in both groups. Treatment with 1500 mg also resulted in an increase in ejaculate quantity in all patients.

** Patients with unilateral or bilateral hypotrophy of the testes and oligospermia demonstrated improvement in ejaculate volume, spermatozoal concentration and motility after treatment (1500 mg/day, 60 days). Testosterone levels were also increased. A light palpable pain in the testicular region with slight edema was reported by patients during the treatment, which abated 2 to 3 months after treatment.

** Treatment of 51 infertile males with 750 mg/day TLSE for 3 months significantly increased ejaculate volume, spermatozoa concentration, motility and velocity. Spermatozoa morphology normalized and ejaculate liquefaction time decreased. Semen immune parameters decreased: leukocyte counts, [alpha]-amylase values (an enzyme involved in ejaculate liquefaction), and secretion of local immunoglobulins. Cholesterol, LDL, triglycerides and VLDL decreased and HDL increased. Libido was normalized or enhanced in those reporting poor libido.

** Thirty-one pregnancies were recorded for 100 couples with infertility involving an immunological cause within 12 months of initiating TLSE treatment. The average time taken to conceive was 5.2 months. Prior to treatment spermatozoa number and quality varied between males, but all males and 74% of females had abnormal results for sperm-agglutinating antibody tests. The dosage used was 750 mg/day for males and 750 mg/day from days 21 to 27 of the menstrual cycle for females until conception.

** Improvement in sperm profile was not observed in patients with chronic prostatitis (750 to 1500 mg/day).

** Of 14 patients suffering reduced libido, 12 showed considerable improvement after 30 days (1500 mg/day) and one patient was slightly improved after 60 days' treatment. Libido was improved in 27 of 36 patients with chronic prostatitis. The other nine patients, with chronic prostatitis for over 5 years, demonstrated no improvement. Libido was incidentally improved in patients with hypotrophy of the testes and idiopathic oligospermia.

** Libido and sexual activity were improved in some patients with Klinefelter's syndrome (genetic hypogonadism), Noonan syndrome (a multifaceted disorder which includes cryptorchidism) and simple cryptorchidism.

** TLSE was well-tolerated in all of the above studies.

Tribulus has been part of a number of herbal formulations successfully used in uncontrolled clinical trials in India and Russia to treat sexual dysfunction or sexual inadequacy in men. The main formulations contained 7 to 12.5% of Tribulus by weight. Improvement in sexual function was observed in convalescing postmyocardial infarction male patients, (33) and in leprosy patients experiencing testicular and epididymal changes. Patients with oligospermia showed objective improvement. (34) Impotence and loss of libido improved in male diabetics. (35) Improvement was observed in men with impotence. (36,37) Sperm count and motility improved in approximately 60 to 70% of subfertile and oligospermic men. (38,39)

Female Infertility

In an open study involving infertile women, TLSE (750 to 1500 mg) was administered every day for 2 to 3 months (Group 1), only on days 5 to 14 of the menstrual cycle for 2 to 3 months (Group 2), or used in the preovulatory phase in combination with an ovulation stimulant for 3 months (Group 3). (15) Group 1 did not show improvement in the ovulation parameters measured and side effects were observed, especially when the treatment was abruptly terminated. Of the 36 women in Group 2, 6% of women experienced normalized ovulation with resultant pregnancy, 61% demonstrated normalized ovulation without pregnancy and 33% demonstrated no effect from treatment. Parallel control studies on a comparable cohort were carried out utilizing three conventional ovulation stimulants. The best results were obtained with 62 women treated using epimestrol: 39% had normalized ovulation with pregnancy, 35% had normalized ovulation without pregnancy and 26% demonstrated no effect from treatment. No side effects were recorded for the TLSE group, compared with an incident rate of 6.5%, 10.6% and 38% in women treated with the ovulation stimulants. For the 20 women treated with TLSE and an ovulation stimulant (Group 3), the effect from their combined use was better than treatment with either single agent.

Menopause

In an open study, 98% of 50 menopausal women experienced some symptom improvement after TLSE treatment, but not after placebo. Fifty-two percent of patients were experiencing natural menopause and 48% had postoperative symptoms after removal of their ovaries. Predominant symptoms included hot flashes, sweating, insomnia and depression. The dosage prescribed varied, but generally a maintenance dose of 500 to 750 mg/day of TLSE was reached after higher initial doses. Treatment did not result in significant changes in FSH, LH, prolactin, estradiol, progesterone and testosterone, although FSH tended to be lower. (15)

Body Composition and Exercise Performance

TLSE given for 8 weeks at a daily dose of 3.21 mg/kg did not enhance body composition or exercise performance in eight resistance-trained males when coupled with a resistance-training program in a randomized, double-blind, placebo-controlled trial. The authors concede that the lack of improvement in body composition in both groups may be attributed to the fact that these subjects were already lean and may not have consumed enough protein or calories to gain lean body mass. In addition, the method chosen to assess exercise performance was not the most objective measure available. (40) The dose of TLSE used was low (240 to 260 mg/day).

Other Conditions

In an open trial of 406 patients with coronary artery disease treated with saponins isolated from Tribulus, improvement was observed for angina pectoris and for ECG readings of myocardial ischemia. The saponin fraction was said to dilate the coronary arteries and improve coronary circulation. No side effects or adverse reactions on blood, hepatic or renal functions were observed. (41)

Mechanism of Action

TLSE (750 mg/day for 5 days) increased serum FSH and estradiol compared to baseline values in human female volunteers and increased the level of LH and testosterone in male volunteers, (42) thus demonstrating increased sex hormone production in both men and women. In other words, the sexual and tonic activities of Tribulus may not result from a direct hormonal activity of the saponins or direct effects on the gonadal tissue. Instead, they could be mediated at the level of the hypothalamus or pituitary.

It has been suggested in one article that protodioscin is converted in the human body into DHEA. (43) There is no sound evidence to support such a speculation.

Quality Issues

Two studies have highlighted that most Tribulus products on the market are quite different from the Bulgarian extract (TLSE). (44,45) The first study, conducted in the US, found that the level of protodioscin varied substantially with the plant part (leaf, stem or fruit) and origin (Bulgaria, India or China) of the Tribulus. (44) Only leaf from Bulgaria was high in protodioscin. Analysis of products selected from the US market found deficiencies of protodioscin in the majority.

The second study from Australia produced similar results. (45) An Eastern European variety of Tribulus (from Slovakia) contained high levels of protodioscin in the leaf but none in the fruit. Leaf from Australia and India did not contain protodioscin.

The principle of phytoequivalence dictates that, if the benefits demonstrated in a clinical trial are claimed for a herbal product, then that product must closely match the one used in the clinical trial. The Bulgarian clinical trials which have shown that Tribulus boosts libido and fertility and alleviates menopausal symptoms, all used Tribulus leaf rich in protodioscin collected from Bulgaria. Therefore only similar products might reasonably be expected to have the same effects. If a Tribulus product is made from the root or fruit of the plant, or is sourced from anywhere else other than Eastern Europe, it will probably contain low levels of protodioscin and so will be quite different from the Bulgarian standardized extract. This is despite what might be claimed on the label for such products, because often inferior methods of analysis have been used to measure the furostanol saponins, such as gravimetric or colorimetric techniques. The quality of Tribulus products is best assessed by high performance liquid chromatography as used in the two studies cited above.

Clinical Summary

Actions

Tonic, aphrodisiac, estrogenic in females (indirectly), androgenic in males (indirectly), fertility agent.

Recommended Therapeutic Uses

** Male erectile dysfunction

** Male and female infertility

** Menopausal symptoms

** Decreased libido in men and women

** To restore or build vitality (especially during convalescence or after surgery) and to assist in responding to stress; to improve physical performance.

Dosage and Administration

The recommended adult dosage for the hormonal effects is one tablet of standardized concentrate, containing 100 mg of furostanol saponins (calculated as protodioscin), three to four times per day. Higher doses may be necessary in some cases, especially for male impotence.

Suggested Combinations

Tribulus combines well with damiana, Korean ginseng, saw palmetto or ashwaganda (Withania somnifera) in male sexual inadequacy and infertility and low libido in women; black cohosh or wild yam in menopause; and ashwaganda, Eleutherococcus or Korean ginseng for tonic use.

Adverse Reactions

As with all saponin-containing herbs, oral intake may cause esophageal reflux and irritation of the gastric mucous membranes.

Contraindications and Cautions

According to Traditional Chinese Medicine, Tribulus should be used with caution in pregnancy. (46) If Tribulus is being used to promote fertility in women, its use is best stopped after pregnancy is established. While it is unlikely that normal human doses of Tribulus leaf would cause cholestasis, this should be considered in unexplained cases of cholestasis in patients taking Tribulus. Steroidal saponin-containing herbs such as Tribulus are best kept to a minimum in patients with pre-existing cholestasis.

Male Infertility: Clinical Anecdotes

These have been provided by Dr. Therese Lovell, MD. (47)

Case 1

A 42-year-old male with very low sperm count, 38% abnormal forms and poor motility. No pregnancy with unprotected sex (same partner) for last 7 years.

Therapy: One tablet* b.i.d. Wife was pregnant before the 3 months when I planned to repeat his semen analysis.

Case 2

A 59-year-old male unable to fertilize his partner's egg outside of the IVF laboratory using ICSI (intracytoplasmic sperm injection). To date only one successful pregnancy resulted from ICSI which miscarried before/at 9 weeks.

Therapy: One tablet* b.i.d. At the 3 month review week we discovered his partner is pregnant ... with no IVF intervention! A natural cycle, spontaneous insemination had occurred.

Acknowledgments

The contribution of Michelle Morgan and Janice McMillan in the preparation of this article in gratefully acknowledged.

*This tablet contained Tribulus terrestris herb, standardized for 100 mg furostanol saponins as protodioscin.

References

1. Kapoor LD, CRC Handbook of Ayurvedic Medicinal Plants. Boca Raton: CRC Press, 1990; p 325

2. Frawley D, Lad V. The Yoga of Herbs: An Ayurvedic Guide to Herbal Medicine, 2nd Edition. Santa Fe: Lotus Press, 1988: pp 169-170

3. Thakur RS, Puri HS, Husain A. Major Medicinal Plants of India. Lucknow: Central Institute of Medicinal and Aromatic Plants, 1989: pp 506-509

4. Bensky D, Gamble A. Chinese Herbal Medicine Materia Medica. Seattle: Eastland Press, 1986: pp 607-608

5. Gjulernetowa R, Tomowa M, Simowa M et al. Pharmazie 1982; 37: 296

6. Tomova M, Gyulemetova R, Zarkova S et al. Int Conf Chem Biotechnol Biol Act Nat Prod (Proc) 1st. 1981; 3: 298

7. Yan W, Ohtani K, Kasai R et al. Phytochem 1996; 42: 1417

8. Mahato SB, Sahu NP, Ganguly AN et al. J Chem Soc Perk Trans 1981; 1: 2405

9. Bourke CA, Stevens GR, Carrigan MJ. Aust Vet J 1992; 69: 163

10. Personal communication from Dr R Lehmann, General Manager Research & Development, MediHerb Research Laboratories, September 2004.

11. Hostettmann K, Marston A, Chemistry & Pharmacology of Natural Products: Saponins. Cambridge: Cambridge University Press, 1995.

12. Zarkova S. Rev Port Ciencias Vet 1984; 79: 117

13. Georgiev P, Dimitrov M, Vitanov S. Vet Sb 1988; 3: 20

14. Dimitrov M, Georgiev P, Vitanov S. Vet Med Nauki 1987; 24: 102

15. Zarkova S. Tribestan: Experimental and Clinical Investigations. Chemical Pharmaceutical Research Institute, Sofia, Bulgaria.

16. Gautharnan K, Adaikan PG, Prasad RN. Life Sci 2002; 71: 1385

17. Gauthaman K, Ganesan AP, Prasad RN. J Altern Complement Med 2003; 9: 257

18. Toshkov A, Dimov V, Zarkova S. MBI: Medicobiologic Information 1985; p 28

19. Taskov M. MBI: Medicobiologic Information 1988; 1: 3

20. Taskov M. MBI: Medicobiologic Information 1988; 1: 4

21. Tyutyulkova N, Taskov M, Manolova B. MBI: Medicobiologic Information 1988; 6: 27

22. Dikova N, Ognyanova V. Anniversary Scientific Session: 35 Years Chemical Pharmaceutical Research Institute, Sofia, Bulgaria, March 22-23, 1983.

23. Tanev G, Zarkova S. Toxicological studies on Tribestan, cited in Zarkova S. Tribestan: Experimental and Clinical Investigations. Chemical Pharmaceutical Research Institute, Sofia, Bulgaria.

24. Gendzhev Z. Tr Nauchnoizsled Khim Farm Inst 1985; 15: 241-250

25. Tapia MO, Giordano MA, Gueper HG. Vet Hum Toxicol 1994; 36(4): 311-313

26. Glastonbury JR, Doughty FR, Whitaker SJ et al. Aust Vet J 1984; 61(10): 314-316

27. Waller GR, Yamasaki K (eds). Saponins used in Food and Agriculture. Advances in Experimental Medicine and Biology, Volume 405. New York: Plenum Press, 1996: pp 381-382

28. Protich M, Tsvetkov D, Nalbanski B et al. Akush Ginekol 1983; 22: 326

29. Kumanov F. Bozadzhieva E, Andreeva M et al. Savr Med 1982; 4: 211

30. Viktorov IV, Kaloyanov AL, Lilov L et al. MBI: Medicobiologic Information 1982, cited in Zarkova S. Tribestan: Experimental and Clinical Investigations. Chemical Pharmaceutical Research Institute, Sofia, Bulgaria.

31. Nikolova V, Stanislavov R. Dokl Bolg Akad Nauk 2000; 53: 113

32. Stanislavov R, Nikolova V. Dokl Bolg Akad Nauk 2000; 53: 107

33. Nikolaeva LF, Dedov II, Kurbanov VA. Kardiologiia 1986; 26: 82

34. Nigam P, Mukhija RD, Gupta AK et al. Hansenol Int 1984; 9: 10

35. Sathyanathan TJ. Indian Med Gaz 1985; 119: 196

36. Sankaran JR. J Natl Integ Med Ass 1984; 26: 315

37. Misra DN, Shukla GD. Indian Med Gaz 1984; 118: 322

38. Pardanani DS, Delima RJ, Rao RV et al. Indian J Surg 1976; 38: 34

39. Dandapat MC, Mohapatro SK, Patro SK. Indian Med Gaz 1985; 119: 14

40. Antonio J, Uelmen J, Rodriguez R et al. Int J Sport Nutr Excer Metab 2000; 10: 280

41. Wang B, Ma L, Liu T. Chung His I Chieh Ho Tsa Chih 1990; 10: 85

42. Milanov S, Maleeva E, Taskov M. MBI: Medicobiologic Information 1985; 4: 27

43. Adimoelja A. Int J Androl 2000; 23 Suppl 2 82-84

44. Ganzera M, Bedir E, Khan IA. J Pharm Sci 2001; 90: 1752

45. Lehmann RP, Penman KG, Halloran KG. Revista de Fitoterapia 2002; 2(S1): 217 (Abstract B006)

46. Bensky D, Gamble A, Chinese Herbal Medicine Materia Medica. Seattle: Eastland Press, 1986.

47. Lovell T. Modern Phytotherapist 2001; 6(2): 21

by Kerry Bone, FNIMH, FNHAA

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FNIMH = Fellow, National Institute of Medical Herbalists (UK)

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